Relationship Between Histological Stage and Neutrophil to Lymphocyte Ratio in Chronic Hepatitis C

Objective: The histological stage is crucial for the management of patients with chronic hepatitis C. Because invasiveness and some limitations liver biopsy a lot noninvasive tests are in search intensively to use instead biopsy. In this study, we searched relationship neutrophil lymphocyte ratio inflammation fibrosis histology Materials Methods: This study retrospectively investigated datas 62 C 40 healthy controls. Results: Mean values control groups were 1.86 (0.89-3.94) 1.38 (0.73-2.93) respectively (p=0.001). group there 23 (%37) advanced (Ishak score>2) 39 (%63) mild score≤ 2). fibrosis, mean was high according (2.10 (1.21-3.54) 1.71(0.89-3.94) respectively, p=0.006). receiver operating characteristic (ROC) curve analysis, cut off value 1.76 (sensitivity 86.9%, specifity 61.5%, NPV 88.9%, PPV 57.1%, AUC: 0.711). Conclusion: Neutrophil can predict But more studies necessary clinic practice or how parameter change treatment.